Next-generation psychedelic workers

Presented by The Michael J. Fox Foundation for Parkinson's Research: The ideas and innovators shaping health care
May 01, 2024 View in browser
 
Future Pulse

By Erin Schumaker, Daniel Payne, Carmen Paun and Ruth Reader

Presented by 

The Michael J. Fox Foundation for Parkinson's Research
WORKFORCE

A woman demonstrates what a patient would experience in a therapy room at Field Trip, a psychedelic therapy clinic in as medical director Dr. Michael Verbora waits by her side in Toronto, Ontario, Canada, on August 28, 2020. (Photo by Cole BURSTON / AFP) (Photo by COLE BURSTON/AFP via Getty Images)

Psychedelic therapy could be a growth industry judging by a new training program. | AFP via Getty Images

Social workers are prepping for the psychedelic revolution.

The Food and Drug Administration has set a target date of Aug. 11 for a decision on the first drug application for talk therapy combined with MDMA, commonly called ecstasy, as a treatment for post-traumatic stress disorder. Should the FDA approve Lykos Therapeutics’ application, universities that train social workers, psychologists and psychiatrists want to be ready.

The Columbia University School of Social Work is rolling out a 25-person psychedelic-assisted training program this fall, which includes 120 hours of classroom coursework and 600 hours of clinical experience in a ketamine clinic.

Unlike independent training programs, which can run thousands of dollars per course, Columbia isn’t charging its masters’ students extra, said Heidi Allen, the school’s associate dean for research.

Why it matters: There’s already a lack of mental health providers, with half of the U.S. population living in areas that have a shortage, according to a report by the National Center for Health Workforce Analysis.

“Without addressing the fundamental drivers of access to care, innovative new treatments simply widen existing disparities,” Allen told Erin.

Wide angle: Last month, the nonprofit mental health advocacy group BrainFutures hosted a roundtable in New York that brought together representatives from disciplines like nursing, psychiatry and psychology from 10 universities, including Columbia, to share the models and curricula they’re developing for psychedelic-assisted therapy and to learn from one another.

Even so: There’s no guarantee the FDA will approve the therapy/MDMA application. The Institute for Clinical and Economic Review, an independent, nonpartisan expert review panel, painted a negative picture of Lykos’ application in a draft report released in March. However, the group said the draft shouldn’t be interpreted as a final assessment of the treatment as it still has more evidence to review.

Flags raised by the report included safety, ethical and cost concerns. The report also projected difficulty in widely implementing the treatment.

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THE LAB

NEW YORK - DECEMBER 1:  Marina Kemelman, Research Associate at the AIDS Vaccine Design and Development Laboratory,  collects bacteria transfected with DNA as part of research at the laboratory's campus in the former Brooklyn Army Terminal December 1, 2008 in New York City.  The laboratory, seeking a vaccine to prevent the spread of AIDS, is part of the International AIDS Vaccine Initiative (or   IAVI), a global not-for-profit, public-private partnership working to accelerate the development of a vaccine to prevent HIV infection and AIDS.  December 1 is the 20th annual World AIDS Day around the world.  (Photo by Chris Hondros/Getty Images)

AI may offer new hope to those suffering from genetic disorders, a study found. | Getty Images

Artificial intelligence can help diagnose genetic disorders, improving the accuracy of traditional diagnostic methods, according to new research published in NEJM AI.

How so? Researchers from Texas Children’s Hospital and Baylor University used a machine-learning program trained on 3.5 million variants from diagnosed cases.

The system identified 57 percent of diagnosable cases, the authors found, with a 98 percent precision rate. (The current diagnostic accuracy rate for genetic disorders is estimated at 30-40 percent.)

Even so: The system has limitations: It can’t analyze certain types of genetic variations.

That could change if it’s integrated with other language-focused AI systems, the authors suggest.

Why it matters: The program offers hope to patients whose diseases haven’t been diagnosed through traditional methods and could help scientists identify new disease-causing genes.

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EXAM ROOM

MADRID, SPAIN - JUNE 06: A doctor shows on a computer screen a positive result of monkeypox test at the microbiology laboratory of La Paz Hospital on June 06, 2022 in Madrid, Spain. Europe is at the centre of the monkeypox virus outbreak, the World Health Organisation reported 780 confirmed cases with Britain, Spain and Portugal reporting the largest numbers of patients. (Photo by Pablo   Blazquez Dominguez/Getty Images)

When it comes to coding medical bills, a human better remain in the loop for now, researchers found. | Getty Images

Health providers are enthusiastic about advanced artificial intelligence’s potential to tabulate their work so they can bill insurers more efficiently.

But a new study in NEJM AI suggests caution about AI’s usefulness in clinical coding. The researchers found the AI models they tested were prone to making big mistakes.

How so? Researchers at the Icahn School of Medicine at Mount Sinai in New York City, Tel Aviv University and Sheba Medical Center in Israel found that the models — OpenAI’s GPT-3.5 and GPT-4, Google’s Gemini Pro and Meta’s LLaMa2-70b Chat — miscoded work regularly.

GPT-4’s coding was more accurate than the other models, but even so, its codes were incorrect in most cases. Depending on the coding system, GPT-4 chose the correct code between 30 percent and 50 percent of the time.

All the systems were prone to creating nonexistent codes.

The researchers said the large-language models shouldn’t be used for medical coding without further research and improvements.

Even so: Some companies are developing systems tailored to work in a medical environment with hopes they could be more reliable than the offerings in the study.

And some AI and health researchers have suggested that problems could be resolved relatively quickly.

 

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